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ENROLLING BY INVITATION
NCT07186881

Evolving Diagnostic Approaches to Undocumented Lymphocytic Meningitis and Meningoencephalitis

Sponsor: Central Hospital, Nancy, France

View on ClinicalTrials.gov

Summary

Tick-borne encephalitis (TBE) is a viral infection transmitted by ticks. TBE is the third most common cause of encephalitis in France. Across France, numerous cases of lymphocytic meningitis remain without a definitive diagnosis, notably at the Nancy University Hospital. The objective of this study is to assess the impact of a change in diagnostic practice on the work-up of undocumented lymphocytic meningitis and meningoencephalitis at Nancy University Hospital.

Official title: Effect of Changes in Diagnostic Protocols for Unexplained Lymphocytic Meningitis and Meningoencephalitis : A Retrospective Single-centre Study

Key Details

Gender

All

Age Range

Any - Any

Study Type

OBSERVATIONAL

Enrollment

200

Start Date

2022-08-15

Completion Date

2026-08-15

Last Updated

2025-09-22

Healthy Volunteers

No

Interventions

OTHER

Recommendation from the infectious diseases team

No commercial product was evaluated in this study. We are assessing the benefits and consequences of a change in clinical practice implemented at the hospital level. At our institution, it is now recommended that TBE serology be performed in all cases of undocumented meningitis or meningoencephalitis. The infectious diseases team at our hospital simply advises the clinicians responsible for patient care to perform this test.

Locations (1)

University Hospital of Nancy, Brabois Hospital

Vandœuvre-lès-Nancy, Lorraine, France