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RECURrence of Atrial Fibrillation After Cardioversion of Patients Randomized to Dapagliflozin or Usual Care
Sponsor: Region Stockholm
Summary
The goal of this clinical trial is to learn if drug dapagliflozin, a sodium-glucose transport-2 inhibitor, works to treat atrial fibrillation in adults. The main question it aims to answer is: • Does the drug dapagliflozin reduce the recurrence rate of atrial fibrillation? Researchers will compare drug dapagliflozin to standard therapy to see if drug dapagliflozin reduce the recurrence of atrial fibrillation. Persons with atrial fibrillation who are planned for an electric cardioversion will: * Take the drug dapagliflozin, or no drug, once a day for a maximum of 56 days * Undergo a planned electric cardioversion of the atrial fibrillation * Record the rhythm with a hand-held device that transmits the signal to researchers during the study period, but no longer than for 56 days
Official title: RECURrence of Atrial Fibrillation After Cardioversion of Patients Randomized to Open-label Treatment With Dapagliflozin or Usual Care
Key Details
Gender
All
Age Range
55 Years - Any
Study Type
INTERVENTIONAL
Enrollment
1600
Start Date
2025-06-03
Completion Date
2027-12
Last Updated
2025-09-23
Healthy Volunteers
No
Conditions
Interventions
Dapagliflozin 10 mg once daily
Tablet Dapagliflozin 10 mg orally during from randomization for maximum 56 days.
Locations (7)
Linköping university hosptial
Linköping, Sweden
Örebro University hospital
Örebro, Sweden
Södersjukhuset
Stockholm, Sweden
Karolinska University Hospital
Stockholm, Sweden
Danderyds Hospital
Stockholm, Sweden
Norrlands universitetssjukhus
Umeå, Sweden
Akademiska sjukhuset
Uppsala, Sweden