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RECRUITING
NCT07187570
PHASE3

RECURrence of Atrial Fibrillation After Cardioversion of Patients Randomized to Dapagliflozin or Usual Care

Sponsor: Region Stockholm

View on ClinicalTrials.gov

Summary

The goal of this clinical trial is to learn if drug dapagliflozin, a sodium-glucose transport-2 inhibitor, works to treat atrial fibrillation in adults. The main question it aims to answer is: • Does the drug dapagliflozin reduce the recurrence rate of atrial fibrillation? Researchers will compare drug dapagliflozin to standard therapy to see if drug dapagliflozin reduce the recurrence of atrial fibrillation. Persons with atrial fibrillation who are planned for an electric cardioversion will: * Take the drug dapagliflozin, or no drug, once a day for a maximum of 56 days * Undergo a planned electric cardioversion of the atrial fibrillation * Record the rhythm with a hand-held device that transmits the signal to researchers during the study period, but no longer than for 56 days

Official title: RECURrence of Atrial Fibrillation After Cardioversion of Patients Randomized to Open-label Treatment With Dapagliflozin or Usual Care

Key Details

Gender

All

Age Range

55 Years - Any

Study Type

INTERVENTIONAL

Enrollment

1600

Start Date

2025-06-03

Completion Date

2027-12

Last Updated

2025-09-23

Healthy Volunteers

No

Interventions

DRUG

Dapagliflozin 10 mg once daily

Tablet Dapagliflozin 10 mg orally during from randomization for maximum 56 days.

Locations (7)

Linköping university hosptial

Linköping, Sweden

Örebro University hospital

Örebro, Sweden

Södersjukhuset

Stockholm, Sweden

Karolinska University Hospital

Stockholm, Sweden

Danderyds Hospital

Stockholm, Sweden

Norrlands universitetssjukhus

Umeå, Sweden

Akademiska sjukhuset

Uppsala, Sweden