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Immunometabolism of Exercise
Sponsor: University of Houston
Summary
This study aims to examine the effects of acute aerobic exercise and cardiorespiratory fitness on cellular metabolism of CD8+ T cells and regulatory T cells (Tregs) found in the peripheral blood of humans. In addition, the study will investigate whether the effects of exercise differ based on exercise intensity, as well as whether the effects of exercise and fitness differ between subpopulations of CD8+ T cells and Tregs. Finally, the study aims to examine whether exercise- and fitness-induced changes in cell metabolism relate to changes in cell function.
Official title: Immunometabolism of Exercise and Fitness
Key Details
Gender
All
Age Range
20 Years - 40 Years
Study Type
INTERVENTIONAL
Enrollment
102
Start Date
2024-03-01
Completion Date
2025-04-03
Last Updated
2026-05-01
Healthy Volunteers
Yes
Interventions
Acute exercise-moderate intensity
30 minutes of cycling exercise at moderate (90% of first ventilatory threshold)
Acute effects-heavy intensity
Participants will cycle 30 minutes at heavy (110% of first ventilatory threshold) intensity
Locations (1)
University of Houston
Houston, Texas, United States