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Prilocaine for Sphenopalatine Ganglion Block in Endoscopic Hypophysectomy
Sponsor: Kasr El Aini Hospital
Summary
Patients undergoing endoscopic surgeries for pituitary adenoma excision suffer from wide swings in blood pressure that might increase bleeding and interfere with the surgical field. Local anethetic infiltration and regional nerve blocks have been used to provide better analgesia, control blood pressure and improve surgical field. Limited studies evaluated shenopalatine ganglion block in pituitary adenoma excision with promising outcomes. The proposed study will compare the efficacy of two local anesthetics, prilocaine and lidocaine, for spenopalatine ganglion block in patients undergoing endoscopic pituitary adenoma excision. Evaluating the control of the intraoperative blood pressure and analgesic sparing are the main objectives of the proposed study.
Official title: Bilateral Sphenopalatine Ganglion Block Using Prilocaine Versus Lidocaine as Adjuvants to General Anesthesia During Endoscopic Hypophysectomy, Randomized Trial.
Key Details
Gender
All
Age Range
21 Years - 45 Years
Study Type
INTERVENTIONAL
Enrollment
54
Start Date
2025-12-01
Completion Date
2026-02
Last Updated
2025-12-05
Healthy Volunteers
No
Conditions
Interventions
Sphenopalatine Ganglion Block using 2% lidocaine
Sphenopalatine ganlion block with 2ml of 2% lidocaine and 0.5ml of diluted adrenaline after general anesthesia in patients undergoing enoscopic hypophysectomy.
Sphenopalatine Ganglion Block
Sphenopalatine ganlion block with will receive 2ml of 4% prilocaine and 0.5ml saline after general anesthesia in patients undergoing enoscopic hypophysectomy.
Sphenopalatine Ganglion Block
Sphenopalatine ganlion block with will receive 2ml of 4% prilocaine in addition to 0.5ml of diluted adrenaline. after general anesthesia in patients undergoing enoscopic hypophysectomy.
Locations (1)
Kasr El Ainy
Cairo, Egypt