Clinical Research Directory

Inclusion Criteria: * Parkinson's disease diagnosis according to MDS criteria (Postuma et al., 2015) * Disease duration ranging from 5 to 10 years * Age 40-80 * Patients in stages 2 and 3 of the Hoehn and Yahr (a functional disability scale) in the ON condition * The participant is using a compatible smartphone * Written informed consent Exclusion Criteria: * Atypical Parkinsonian Syndrome * Second-line device-aided treatments * Patients with \>4 daily doses of L-DOPA * Daily levodopa equivalent dose \> 1500 mg * Ongoing hallucinations requiring short-term treatment adjustment * Inability to provide informed consent or participate in the study * Inability to use the smartwatch and/or the mAI-Care app - as judged by investigator * Lacking motivation to participate in study procedures - as judged by investigator * Under adult autonomy protection system, legal guardianship or incapacitation * Pregnant and breast-feeding women