Clinical Research Directory
Browse clinical research sites, groups, and studies.
Time Restricted Eating for WeIght LoSs MainTenance-2
Sponsor: NYU Langone Health
Summary
The TWIST 2.0 Study is a 12-month, 2-arm RCT in adults with recent weight loss. We will examine the efficacy of TRE on weight (Aim 1a) and fat mass (Aim 1b) regain, and describe changes in subjective appetite following a mixed-meal tolerance test (Exploratory).
Official title: Time Restricted Eating for WeIght LoSs MainTenance-2 (TWIST-2): A Single-site, 2-arm Randomized Clinical Trial in Adults With Recent Weight Loss
Key Details
Gender
All
Age Range
25 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
110
Start Date
2025-10-01
Completion Date
2028-01-01
Last Updated
2025-12-26
Healthy Volunteers
No
Interventions
TRE
Participants randomized to the TRE arm will be instructed to consume all food and beverages in a self-selected 10-hr eating window.
Weight-Loss Maintenance Advice
The CON arm participants will receive written baseline advice following randomization assignment that includes determinants associated with long-term weight-loss maintenance success (e.g., physical activity, and strategies to limit calorie intake).
Locations (1)
NYU Langone Health
New York, New York, United States