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RECRUITING
NCT07190170
NA

Time Restricted Eating for WeIght LoSs MainTenance-2

Sponsor: NYU Langone Health

View on ClinicalTrials.gov

Summary

The TWIST 2.0 Study is a 12-month, 2-arm RCT in adults with recent weight loss. We will examine the efficacy of TRE on weight (Aim 1a) and fat mass (Aim 1b) regain, and describe changes in subjective appetite following a mixed-meal tolerance test (Exploratory).

Official title: Time Restricted Eating for WeIght LoSs MainTenance-2 (TWIST-2): A Single-site, 2-arm Randomized Clinical Trial in Adults With Recent Weight Loss

Key Details

Gender

All

Age Range

25 Years - 65 Years

Study Type

INTERVENTIONAL

Enrollment

110

Start Date

2025-10-01

Completion Date

2028-01-01

Last Updated

2025-12-26

Healthy Volunteers

No

Interventions

BEHAVIORAL

TRE

Participants randomized to the TRE arm will be instructed to consume all food and beverages in a self-selected 10-hr eating window.

BEHAVIORAL

Weight-Loss Maintenance Advice

The CON arm participants will receive written baseline advice following randomization assignment that includes determinants associated with long-term weight-loss maintenance success (e.g., physical activity, and strategies to limit calorie intake).

Locations (1)

NYU Langone Health

New York, New York, United States