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RECRUITING
NCT07190625
EARLY_PHASE1

Intranasal Versus Intravenous Fentanyl For Procedural Analgesia in Preterm Neonates

Sponsor: Ain Shams University

View on ClinicalTrials.gov

Summary

Pain in neonatal life has profound long-term developmental impacts, so pain control is crucial. The intranasal (IN) route is a minimally invasive method for rapidly delivering fentanyl to provide short-term analgesia and sedation in adults and pediatrics, but few data exist about its use in neonates. Meanwhile, intravenous fentanyl is widely used in sedation and pain management. Using intranasal fentanyl as an analgesic in preterm neonates may provide a rapid, effective, noninvasive route for administration.

Official title: Intranasal Versus Intravenous Fentanyl For Procedural Analgesia in Preterm Neonates : A Randomized Controlled Trial

Key Details

Gender

All

Age Range

Any - 28 Days

Study Type

INTERVENTIONAL

Enrollment

75

Start Date

2023-12-24

Completion Date

2026-06-01

Last Updated

2025-10-01

Healthy Volunteers

No

Conditions

Interventions

DRUG

fentanyl intravenous

giving intravenous fentanyl

DRUG

Fentanyl intranasal using atomizer

giving intranasal fentanyl using nasal atomizer

DRUG

fentanyl intranasal direct

giving intranasal fentanyl directly into nostrils

Locations (1)

Ain Shams University

Cairo, Egypt