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SSSI Efficacy With iACB and PC-LIA in TKA Pain Management
Sponsor: Taipei Medical University WanFang Hospital
Summary
This prospective, triple-blinded, sham-controlled randomized trial evaluates the additive effect of Supra-Sartorial Subcutaneous Infiltration (SSSI) combined with intermittent adductor canal block (iACB) and posterior capsule local infiltration analgesia (PC-LIA) for pain management in total knee arthroplasty (TKA). SSSI, a simpler alternative to targeted anterior femoral cutaneous nerve (AFCN) block, is tested in 90 adults (45-90 years) randomized into two arms: sham SSSI + active iACB + PC-LIA versus all active interventions. Primary outcome is pain scores on postoperative day 0; secondary outcomes include daily pain trajectory, opioid use, functional recovery, and complications over days 0-3.
Official title: Assessment of Supra-Sartorial Subcutaneous Infiltration (SSSI) Efficacy When Combined With Intermittent Adductor Canal Block (iACB) and Posterior Capsule Local Infiltration Analgesia (PC-LIA) in Multimodal Pain Management for Total Knee Arthroplasty: A Randomized Controlled Trial
Key Details
Gender
All
Age Range
45 Years - 90 Years
Study Type
INTERVENTIONAL
Enrollment
90
Start Date
2026-06
Completion Date
2027-07
Last Updated
2026-04-01
Healthy Volunteers
No
Interventions
Supra-Sartorial Subcutaneous Infiltration (SSSI)
20 mL ropivacaine or saline infiltrated lateral-to-medial subcutaneously above sartorius at femoral triangle apex using inject-as-you-advance technique, avoiding hyperechoic nerves.
intermittent adductor canal block (iACB)
An adductor canal catheter is inserted proximal-to-distally over a distance of 6-10 cm at femoral triangle apex, with an initial bolus of 10 mL of 0.3% ropivacaine administered in PACU. The following doses start at 9:00 PM on the day of surgery and are repeated every 12 hours,
posterior capsule local infiltration analgesia (PC-LIA)
PC-LIA consists of two 10 mL injections of 0.3% ropivacaine delivered intraoperatively to the posteromedial and posterolateral aspects of the posterior capsule before cementation. The target injection plane is the potential space between the posterior capsule and the popliteal artery.