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Comparative Analysis of NTG-Pd/Pa and Saline-Pd/Pa (CANS)
Sponsor: National Taiwan University Hospital
Summary
The goal of this observational study is to compare the value of NTG-Pd/Pa and saline-Pd/Pa in participants with intermediate stenosis of the coronary artery. The main questions it aims to answer are: The numerical difference between NTG-Pd/Pa and saline-Pd/Pa To compare the diagnostic performance of NTG-Pd/Pa and saline-Pd/Pa in predicting the binary result of FFR assessment? Participants will undergo NTG-Pd/Pa, Saline-Pd/Pa, and FFR successively in the target vessel.
Official title: A Prospective, Multicenter Study: Comparative Analysis of NTG-Pd/Pa and Saline-Pd/Pa
Key Details
Gender
All
Age Range
21 Years - Any
Study Type
OBSERVATIONAL
Enrollment
50
Start Date
2025-09-17
Completion Date
2029-12-31
Last Updated
2025-09-29
Healthy Volunteers
No
Conditions
Interventions
NTG-Pd/Pa measurement
The coronary artery with intermediate stenosis will sequentially undergo NTG-Pd/Pa, saline-Pd/Pa, and FFR assessments. Intracoronary NTG dosage will follow the protocol based on blood pressure.
Saline-Pd/Pa measurement
The coronary artery with intermediate stenosis will sequentially undergo NTG-Pd/Pa, saline-Pd/Pa, and FFR assessments. Ten millilitres of intracoronary saline will be given over five seconds.
Locations (3)
National Taiwan University Hospital Hsin-Chu Hospital
Hsinchu, Select, Taiwan
Miaoli General Hospital, Ministry of Health and Welfare
Miaoli, Taiwan
Taichung Veterans General Hospital
Taichung, Taiwan