Clinical Research Directory

Inclusion Criteria: * Male and female participants between 18 and 80 years old. * Primary ITP for \>3 months. * An average of two platelet counts (⩾ 7 days apart) of \< 30 × 10⁹/L. * Have relapsed or treatment-resistant to previous ITP therapies, including corticosteroids and at least one other ITP therapy. * Have history of response to previous treatments. * Adequate hematologic, hepatic, and renal fuction. * Participants willing to comply with contraceptive restrictions. Exclusion Criteria: * Diagnosed with secondary immune thrombocytopenia, or there is evidence that the patient has a secondary cause of immune thrombocytopenia. * Previous or current therapy and comedications meet exclusion criteria. * Patients with major caridiovascular disease, active infetion, maligancy or uncontrolled systemic disease. * Women who are breast feeding. * History of hypersensitivity to sudy drug with a similar chemical structure or class. * Previously received JAK inhibitors.