Clinical Research Directory
Browse clinical research sites, groups, and studies.
Efficacy And Safety Evaluation of Glepaglutide in Treatment of SBS
Sponsor: Zealand Pharma
Summary
The purpose of the present Phase 3 trial is to confirm the efficacy and safety of glepaglutide 10 mg twice weekly in a patient population with SBS-IF and generate additional long-term safety data. Glepaglutide is the International Nonproprietary Name and United States Adopted Name (USAN) for ZP1848.
Official title: A Phase 3, Double-blind, Randomized, Parallel Group, Placebo-controlled, Multicenter Trial to Confirm the Efficacy and Safety of Glepaglutide 10 mg Twice Weekly, Followed by a Long-term, Open-label Safety Evaluation in Patients With Short Bowel Syndrome-intestinal Failure (SBS-IF)
Key Details
Gender
All
Age Range
18 Years - 90 Years
Study Type
INTERVENTIONAL
Enrollment
90
Start Date
2026-02-11
Completion Date
2032-02-28
Last Updated
2026-03-30
Healthy Volunteers
No
Conditions
Interventions
Glepaglutide
Subcutaneous (SC) injections twice weekly
Placebo
SC injections twice weekly
Locations (19)
Washington University Center for Advanced Medicine
St Louis, Missouri, United States
New York Presbyterian Hospital-Columbia University Medical Center
New York, New York, United States
Universitätsklinikum AKH Wien
Vienna, Vienna, Austria
Rigshospitalet-Blegdamsvej 9
Copenhagen, Denmark
AP-HP - Hôpital Beaujon
Clichy, France
Universitätsmedizin Rostock
Rostock, Mecklenburg-Vorpommern, Germany
Eugastro Klinische Studien GmbH
Leipzig, Saxony, Germany
Charité - Universitätsmedizin Berlin
Berlin, Germany
Universitätsklinikum Bonn
Bonn, Germany
Asklepios Klinik St. Georg
Hamburg, Germany
Fondazione Policlinico Universitario A. Gemelli IRCCS - PPDS
Rome, Lazio, Italy
Radboud Universitair Medisch Centrum
Nijmegen, Gelderland, Netherlands
Oslo Universitetssykehus HF, Ullevål
Oslo, Norway
Wojewodzki Specjalistyczny Szpital im. M. Pirogowa w Lodzi
Lodz, Lódzkie, Poland
Hospital General Universitario Gregorio Marañon
Madrid, Spain
Hospital Universitario 12 de Octubre
Madrid, Spain
Hospital Universitario Virgen del Rocio - PPDS
Seville, Spain
Sahlgrenska Universitets sjukhuset
Gothenburg, Sweden
Karolinska Universitetssjukhuset Solna
Solna, Sweden