Clinical Research Directory
Browse clinical research sites, groups, and studies.
Evaluation of a Vaccine Chatbot on HPV Vaccine Confidence and Hesitancy
Sponsor: Fudan University
Summary
The goal of this clinical trial is to learn if a chatbot powered by artificial intelligence works to improve HPV vaccination among females aged 15 to 26 in China. A randomized controlled trial and implementation science study will be conducted targeting females as participants. The main questions it aims to answer are: 1. Does the vaccine chatbot influence women's confidence, literacy, hesitancy, and uptake of the HPV vaccine. 2. What are the public acceptance of chatbot and the facilitators and barriers to its implementation in a real-world setting. Researchers will compare a group of women who use the chatbot with a group who do not use it to see if the chatbot is effective at helping women feel confident and willing to get vaccinated against HPV. Participants will: 1. Be recruited and randomly allocated into one of two groups. One group will be invited to use the HPV vaccine chatbot and the other group will not get access to the vaccine chatbot until the end of the trial. 2. Complete a questionnaire survey on their confidence, literacy, and hesitancy on the HPV vaccine. 3. Have their vaccination status checked at the end of trial.
Official title: Evaluation of a Vaccine Chatbot on HPV Vaccine Confidence and Hesitancy: a Randomized Controlled Trial and Implementation Science Study
Key Details
Gender
FEMALE
Age Range
15 Years - 26 Years
Study Type
INTERVENTIONAL
Enrollment
1800
Start Date
2025-09-26
Completion Date
2026-05
Last Updated
2025-10-01
Healthy Volunteers
Yes
Conditions
Interventions
LLM-Powered HPV Vaccine Chatbot
A vaccine chatbot delivered via WeChat or a web browser, designed to provide information and health education about the HPV vaccine. The chatbot is powered by large language models and is trained on an expert-validated knowledge base derived from authoritative sources such as the WHO and China CDC to ensure accuracy. The knowledge base is validated by experts. The chatbot engages users in interactive, conversational dialogue to answer questions and address concerns regarding HPV and HPV vaccines.