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Chronic Ingestion of Fructooligosaccharide and Psyllium on Intestinal Transit in Women With Functional Constipation: A Randomized Crossover Trial
Sponsor: Federal University of Minas Gerais
Summary
The goal of this clinical trial is to evaluate the effect of dietary fibers in the treatment of functional constipation in women. It will also assess the potential side effects associated with fiber consumption. The main questions it aims to answer are: * In women with constipation who do not consume adequate dietary fiber, does supplementation help improve bowel function? * Among the fibers studied, is there any hierarchy of effect in the treatment of constipation (i.e., is one more effective than the other)? The researchers will compare the effects of the two dietary fibers against each other and against a control to evaluate their impact. Participants will: * Consume 20 g of fiber daily for 6 days, divided into two doses of 10 g each. * Attend a nuclear medicine visit at the end of each 6-day fiber period to perform scintigraphy. * Keep a daily record of bowel habits and dietary intake.
Official title: Effects of Chronic Ingestion of Fructooligosaccharide and Psyllium on Intestinal Transit Time in Women Diagnosed With Functional Constipation: A Randomized, Crossover, Double-Blind Clinical Trial
Key Details
Gender
FEMALE
Age Range
18 Years - 59 Years
Study Type
INTERVENTIONAL
Enrollment
25
Start Date
2026-03-14
Completion Date
2027-12
Last Updated
2026-03-24
Healthy Volunteers
No
Conditions
Interventions
Psyllium powder
Psyllium powder: soluble fiber gel forming, provided at 20 g per day (two doses of 10 g each)
Fructooligosaccharide
Fructooligosaccharide: prebiotic, provided at 20 g per day (two doses of 10 g each)
Locations (1)
School of Nursing, Federal University of Minas Gerais
Belo Horizonte, Minas Gerais, Brazil