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Risk of Acute Complications With Rocuronium vs Cisatracurium in Patients With Chronic Kidney Disease
Sponsor: The University of Texas Medical Branch, Galveston
Summary
The purpose of the study is to determine which combination of neuromuscular blocking agent and reversal agent is safer to use during anesthesia for patients with chronic kidney disease. The main question it aims to answer is "The use of Cisatracurium with neostigmine leads to less post-operative pulmonary complications than Rocuronium with sugammadex."
Key Details
Gender
All
Age Range
18 Years - 80 Years
Study Type
INTERVENTIONAL
Enrollment
490
Start Date
2025-08-26
Completion Date
2027-08-26
Last Updated
2026-02-23
Healthy Volunteers
Yes
Interventions
Rocuronium
Will be assessing neuromuscular blockade with rocuronium and reversal with sugammadex
Cisatracurium
Will be assessing neuromuscular blockade with neostigmine and reversal with neostigmine
Sugammadex
Will be assessing neuromuscular blockade with rocuronium and reversal with sugammadex
Neostigmine
Will be assessing neuromuscular blockade with neostigmine and reversal with neostigmine
Locations (1)
University of Texas Medical Branch
Galveston, Texas, United States