Clinical Research Directory
Browse clinical research sites, groups, and studies.
Comparative Effectiveness of Tirzepatide Versus Sitagliptin in Individuals at Cardiovascular Risk (TIRZSITA-CVOT)
Sponsor: Brigham and Women's Hospital
Summary
Investigators are building an empirical evidence base for real world data through large-scale emulation of randomized controlled trials. The investigators' goal is to understand for what types of clinical questions real world data analyses can be conducted with confidence and how to implement such studies.
Key Details
Gender
All
Age Range
40 Years - Any
Study Type
OBSERVATIONAL
Enrollment
49065
Start Date
2025-09-19
Completion Date
2025-10-15
Last Updated
2026-04-30
Healthy Volunteers
No
Interventions
Initiation of tirzepatide
New use of tirzepatide dispensing claim is used as the exposure.
Initiation of sitagliptin
New use of sitagliptin dispensing claim is used as the reference.
Locations (1)
Brigham and Women's Hospital
Boston, Massachusetts, United States