Clinical Research Directory

Effect of Dapagliflozin on Interleukin 10 in Sepsis

Sponsor: Minia University

Summary

The goal of this observational study is to learn about the long-term effects of dapagliflozin as anti-inflammatory agents to improve organ dysfunction and decrease mortality on patients of both genders ageing 18 years or above with sepsis. 1ry Outcome: The anti-inflammatory effect of dapagliflozin in patients with sepsis evaluated by: Effect on inflammatory markers (IL-10). 2ry Outcomes: 1. Severity of sepsis evaluated by the SOFA score. 2. Prognostic value of HDL compared to IL-10 for multi organ failure and death in septic patients and their correlation to the severity of sepsis. 3. ICU mortality \&hospital length stay.

Official title: Effect of Dapagliflozin on Interleukin 10 Compared to High Density Lipoprotein As a Prognosis in Septic Patients

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