Clinical Research Directory

Inclusion Criteria: * Female adults (age \>18 years) with at least one of the following: * Macrocalcification(s) detected in x-ray 2D or 3D mammography images * Macrocalcification(s) located next to cyst (or other identifiable landmark on an ultrasound image) * A cyst, mass, or finding detected in diagnostic/screening ultrasound or mammography Exclusion Criteria: (when performing ultrasound imaging only) * Children (age \< 18 years) are excluded (when performing ultrasound imaging with light, i.e., optoacoustic imaging) * Children (age \< 18 years) are excluded * Is pregnant * Has open sores including insect bites, rash, poison ivy, and chafing on the skin of the ipsilateral breast * Is experiencing phototoxicity associated with currently taking, or having taken, photosensitizing agents within the previous 72 hours such as sulfonamides, ampicillin, tetracycline * Is currently undergoing phototherapy * Has a history of any photosensitive disease (e.g., porphyria, lupus erythematosus) or is undergoing treatment for a photosensitive disease and is experiencing photosensitivity