Clinical Research Directory

Inclusion Criteria: * Skeletally mature and age ≥ 18 years of age at the time of surgery * Previously treated with the Karma Fixation System * Has at least 12-months post-surgery imaging obtained including a minimum 2 view x-rays (lateral flexion and lateral extension) and CT scan, or willing to return to obtain imaging * Be willing and able to comply with the study protocol requirements * Be willing to sign the study-specific Informed Consent Document Exclusion Criteria: * Previous fusion or total disc replacement at the index level(s) * Active systemic infection at the index level at the time of surgery * Current active or suspected malignancy, or a cancer diagnosis that was ongoing during the patient's treatment and healing period * Diagnosis of osteomalacia or Paget's bone disease * Currently enrolled in a competing research study * Currently incarcerated \\ * Currently pregnant or plans to become pregnant