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RECRUITING
NCT07208799
PHASE2

Comparison of Submucosal Dexamethasone and Methylprednisolone in Postoperative Sequelae of Parasymphsis Fractures

Sponsor: Nishtar Medical University

View on ClinicalTrials.gov

Summary

The rationale of the current research is to address the limitation of existing knowledge as it is not clear which of the two drugs (Dexamethasone or Methylprednisolone) is more effective in reduction of postoperative sequelae in patient with mandibular parasymphysis fracture. This study fills the gap by providing sound evidence on the preferred steroid option to help clinicians have more data to make decisions and improve patients' health. The result of this research will then be added to the evidence-based protocols for the treatment of parasymphysis fractures.

Official title: Comparison of Effectiveness of Submucosal Dexamethasone and Methylprednisolone in Management of Postoperative Sequelae in Mandibular Parasymphysis Fractures

Key Details

Gender

All

Age Range

18 Years - 40 Years

Study Type

INTERVENTIONAL

Enrollment

72

Start Date

2026-01-03

Completion Date

2026-12-01

Last Updated

2026-04-06

Healthy Volunteers

No

Interventions

DRUG

Dexamethasone

single dose of dexamethasone 8 mg (2 mL) administered submucosally at the surgical site 30 minutes before incision.

DRUG

Methylprednisolone (Corticosteroid)

a single dose of methylprednisolone 40 mg (2 mL) will be administered submucosally at the surgical site 30 minutes before incision.

Locations (1)

Nishtar Institute of Dentistry Multan

Multan, Punjab Province, Pakistan