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Comparison of Submucosal Dexamethasone and Methylprednisolone in Postoperative Sequelae of Parasymphsis Fractures
Sponsor: Nishtar Medical University
Summary
The rationale of the current research is to address the limitation of existing knowledge as it is not clear which of the two drugs (Dexamethasone or Methylprednisolone) is more effective in reduction of postoperative sequelae in patient with mandibular parasymphysis fracture. This study fills the gap by providing sound evidence on the preferred steroid option to help clinicians have more data to make decisions and improve patients' health. The result of this research will then be added to the evidence-based protocols for the treatment of parasymphysis fractures.
Official title: Comparison of Effectiveness of Submucosal Dexamethasone and Methylprednisolone in Management of Postoperative Sequelae in Mandibular Parasymphysis Fractures
Key Details
Gender
All
Age Range
18 Years - 40 Years
Study Type
INTERVENTIONAL
Enrollment
72
Start Date
2026-01-03
Completion Date
2026-12-01
Last Updated
2026-04-06
Healthy Volunteers
No
Interventions
Dexamethasone
single dose of dexamethasone 8 mg (2 mL) administered submucosally at the surgical site 30 minutes before incision.
Methylprednisolone (Corticosteroid)
a single dose of methylprednisolone 40 mg (2 mL) will be administered submucosally at the surgical site 30 minutes before incision.
Locations (1)
Nishtar Institute of Dentistry Multan
Multan, Punjab Province, Pakistan