Clinical Research Directory

Inclusion Criteria: * Ability to understand the study content and voluntarily sign the Informed Consent Form (ICF). * Aged between 18 and 90 years, inclusive, regardless of gender. * Confirmed diagnosis of bullous pemphigoid prior to randomization. * Bullous Pemphigoid Disease Area Index (BPDAI) activity score ≥ 24 points at the screening visit and at randomization. * Weekly average of the Pruritus Numerical Rating Scale (NRS) score ≥ 4 points at randomization. * Karnofsky Performance Status score ≥50% at the screening visit. Exclusion Criteria: * Diagnosis of other forms of pemphigoid or other autoimmune blistering diseases. * Presence of other active skin comorbidities that may interfere with the study evaluations, apart from bullous pemphigoid. * Insufficient washout period for prior treatments. * Any condition that, in the opinion of the investigator, would preclude the subject's participation in the study.