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Early Predictors for Neurological Outcome After Traumatic Spinal Cord Injury
Sponsor: BG Unfallklinik Murnau
Summary
This project investigates early predictors of neurological recovery after traumatic spinal cord injury through three main aims: 1. MAP and vasopressors - determine whether continuous monitoring of mean arterial pressure (MAP) and the use of vasopressors in the ICU influence neurological outcome. 2. Pharmacological interventions - evaluate the impact of other medications, particularly opioids in the acute stage, on recovery. 3. Biomarkers - identify diagnostic and prognostic biomarkers (blood-borne or digital) from routine clinical measurements within the first year after injury. Using high-frequency ICU data and advanced data science methods, the study seeks to provide insights that support individualized treatment strategies and improve outcomes after SCI.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
800
Start Date
2022-07-20
Completion Date
2026-08-30
Last Updated
2025-10-07
Healthy Volunteers
No
Conditions
Locations (1)
BG Trauma Center Murnau
Murnau am Staffelsee, Bavaria, Germany