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RECRUITING
NCT07212361
NA

Infant Microbiota Restoration With Maternal Microbes

Sponsor: University of Helsinki

View on ClinicalTrials.gov

Summary

The goal of this clinical trial is to test the ability of different bacterial products in restoring natural gut microbiota in C-section born infants. The main question it aims to answer is: Do maternally derived strains of bacteria perform better than commercially available probiotic strains in restoring the gut microbiota of C-section born infants? Researchers will compare the gut microbiota of treated infants to that of untreated C-section born infants and untreated vaginally born infants to see if the bacterial treatments cause the microbiota to resemble that of vaginally born infants. Participants will be given a bacterial product orally once daily for either one or four weeks and be asked to collect faecal, urine and saliva samples.

Key Details

Gender

All

Age Range

Any - 50 Years

Study Type

INTERVENTIONAL

Enrollment

100

Start Date

2025-07-17

Completion Date

2035-12-31

Last Updated

2025-10-08

Healthy Volunteers

Yes

Interventions

DIETARY_SUPPLEMENT

Probiotic

Specific infant-adapted commercially available strains or strains isolated from the infant's mother.

OTHER

Placebo

Infant formula without bacteria.

Locations (2)

Helsinki University Hospital

Helsinki, Finland

University of Helsinki

Helsinki, Finland