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Infant Microbiota Restoration With Maternal Microbes
Sponsor: University of Helsinki
Summary
The goal of this clinical trial is to test the ability of different bacterial products in restoring natural gut microbiota in C-section born infants. The main question it aims to answer is: Do maternally derived strains of bacteria perform better than commercially available probiotic strains in restoring the gut microbiota of C-section born infants? Researchers will compare the gut microbiota of treated infants to that of untreated C-section born infants and untreated vaginally born infants to see if the bacterial treatments cause the microbiota to resemble that of vaginally born infants. Participants will be given a bacterial product orally once daily for either one or four weeks and be asked to collect faecal, urine and saliva samples.
Key Details
Gender
All
Age Range
Any - 50 Years
Study Type
INTERVENTIONAL
Enrollment
100
Start Date
2025-07-17
Completion Date
2035-12-31
Last Updated
2025-10-08
Healthy Volunteers
Yes
Conditions
Interventions
Probiotic
Specific infant-adapted commercially available strains or strains isolated from the infant's mother.
Placebo
Infant formula without bacteria.
Locations (2)
Helsinki University Hospital
Helsinki, Finland
University of Helsinki
Helsinki, Finland