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NCT07212543

Low-Flow Desflurane Anesthesia and Its Effects on BIS and Postoperative Cognitive Functions

Sponsor: Dolunay ARIK

View on ClinicalTrials.gov

Summary

This study investigates the effects of low-flow desflurane anesthesia in adult patients undergoing major abdominal surgery. The researchers will examine whether different low-flow strategies: Cause differences in the Bispectral Index (BIS), which measures brain activity during anesthesia, Affect postoperative cognitive functions such as memory and attention. Participants will: Receive desflurane anesthesia during surgery, Have anesthesia delivered at different low-flow rates, Have their BIS values monitored throughout the operation, Complete tests after surgery to evaluate their cognitive functions. This research will help determine the safety of different low-flow strategies and their impact on patients' cognitive recovery after surgery.

Official title: The Effects of Different Low-Flow Desflurane Anesthesia Strategies on Bispectral Index and Postoperative Cognitive Functions in Patients Undergoing Major Abdominal Surgery

Key Details

Gender

All

Age Range

18 Years - 75 Years

Study Type

OBSERVATIONAL

Enrollment

72

Start Date

2025-05-15

Completion Date

2025-12-21

Last Updated

2025-12-09

Healthy Volunteers

Not specified

Interventions

OTHER

Routine anesthesia care (desflurane at different low-flow rates: 0.5, 1.0, 1.5 L/min); no intervention assigned as part of the study.

Routine anesthesia care (desflurane at different low-flow rates: 0.5, 1.0, 1.5 L/min); no intervention assigned as part of the study.

Locations (1)

Dr. Abdurrahman Yurtaslan Oncology Training and Research Hospital

Ankara, YENİMAHALLE, Turkey (Türkiye)