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Metabolic Effects of Short-term Ultra-processed Food Intake (MEST-UPF)
Sponsor: Göteborg University
Summary
The overall aim of this project is to study the effects of short-term high ultra-processed food intake, compared to nutrient- and energy density matched low ultra-processed food (UPF) intake, on energy intake and appetite. A total of 24 men and women who meet all inclusion criteria and none of the exclusion criteria will be invited to participate. A randomized 2\*2 factorial four-way crossover study will be conducted at the Department of Internal medicine and Clinical Nutrition at the University of Gothenburg, comparing a high-UPF meal to a low-UPF meal also with high and/or low energy density. A supervised breakfast meal will be served, and postprandial blood samples and appetite measures will be collected continuously up to 4 hours after the breakfast meal. Subsequently, an ad libitum lunch meal will be served, and energy intake will be recorded.
Official title: Metabolic Effects of Short-term Ultra-processed Food Intake (MEST-UPF): a Randomized Controlled Trial
Key Details
Gender
All
Age Range
18 Years - 50 Years
Study Type
INTERVENTIONAL
Enrollment
24
Start Date
2025-12-01
Completion Date
2026-04-30
Last Updated
2025-12-15
Healthy Volunteers
Yes
Interventions
Meal high in energy density, high in ultra-processed food
Meal high in energy density, high in ultra-processed food
Meal high in energy density, low in ultra-processed food
Meal high in energy density, low in ultra-processed food
Meal low in energy density, high in ultra-processed food
Meal low in energy density, high in ultra-processed food
Meal low in energy density, low in ultra-processed food
Meal low in energy density, low in ultra-processed food
Locations (1)
Department of internal medicine and clinical nutrition, University olf Gothenburg
Gothenburg, Sweden