Clinical Research Directory

Inclusion Criteria: * Age ≥ 60 years. * Self-reported cognitive decline, confirmed by an informant. * Montreal Cognitive Assessment (MoCA) score of 19-25, adjusted for years of education (+1 point for 12 years or less). * Ability to complete activities of daily living independently. * Possesses basic communication skills and is able to cooperate with the study procedures. * Voluntarily agrees to participate in the study and signs the informed consent form. Exclusion Criteria: * Presence of underlying neurological diseases that may impair cognitive function, including but not limited to dementia syndrome, Parkinson's disease, epilepsy, and cerebrovascular disease. * Presence of severe or unstable organic diseases such as cancer, hydrocephalus, history of central nervous system tumors, or acute brain injury/infection. * Diagnosis of severe mental illness such as major depressive disorder, schizophrenia, schizoaffective disorder, or bipolar disorder. * Presence of severe visual or hearing impairment, or other physical conditions that may interfere with the completion of the study. * Participation in any other clinical trial within the past 3 months. * Having received transcranial magnetic stimulation (TMS), transcranial direct current stimulation (tDCS), light therapy, or having taken medications that could significantly affect cognitive function (e.g., nootropics, psychoactive drugs, anticholinergic drugs, benzodiazepines) for any reason within the past 6 months. * History of alcohol dependence or substance abuse. * Consumption of alcohol or other substances that affect cognitive function, such as caffeine or cocaine, within 24 hours prior to the cognitive assessment. Any other conditions that the investigator deems unsuitable for participation in this study.