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RECRUITING
NCT07213375
PHASE2/PHASE3

High Dose Dexamethasone to Reduce Postoperative Pain After Video-Assisted Thoracoscopic Surgery Lobectomy /Segmentectomy

Sponsor: Rigshospitalet, Denmark

View on ClinicalTrials.gov

Summary

The aim is to conduct a randomized controlled trial (RCT) with a high dose arm (1mg/kg) vs a low dose (8mg in total) of steroid (Dexamethasone) given intravenous (IV) after the induction of anesthesia to "High-pain-responders" in patients undergoing VATS lobectomy/segmentectomy. The hypothesis is that a high dose of Dexamethasone can lower pain when coughing in the morning after VATS lobectomy/segmentectomy, in patients scoring as "High-pain-responders" on the Pain-Catastrophizing-Scale

Official title: High Dose Dexamethasone In High-Pain Responders Undergoing Enhanced Recovery Video-Assisted Thoracoscopic Surgery Lobectomy and Segmentectomy - A Randomized Double-Blinded Controlled Trial

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

80

Start Date

2025-09-01

Completion Date

2026-11

Last Updated

2026-01-07

Healthy Volunteers

No

Interventions

DRUG

Dexamethasone

Patients will receive either low dose (8mg) or high dose (1mg/kg)

Locations (1)

Department for Cardiothoracic Surgery, Rigshospitalet

Copenhagen, Copenhagen, Denmark