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Acoustic Resonance Therapy for Treating Empty Nose Syndrome
Sponsor: Stanford University
Summary
This study is to determine whether Acoustic Resonance Therapy (ART), an FDA-approved treatment for standard nasal obstruction, may be helpful in mitigating the debilitating symptoms of Empty Nose Syndrome (ENS), which includes an alternative form of nasal obstruction. ART is a non-invasive treatment that uses sound vibrations to improve nasal congestion and other sinus symptoms. ART works by delivering specific frequencies of sound to the sinonasal cavities (nose and sinuses). These vibrations cause the tissues in the sinuses to resonate, which can help break up mucus and clear blockages, reduce inflammation, and improve airflow.
Official title: Acoustic Resonance Therapy for Treatment of Empty Nose Syndrome: A Prospective, Phase 2 Randomized Clinical Trial
Key Details
Gender
All
Age Range
18 Years - 85 Years
Study Type
INTERVENTIONAL
Enrollment
40
Start Date
2028-07
Completion Date
2030-07
Last Updated
2025-10-10
Healthy Volunteers
No
Conditions
Interventions
Personalized ART
ART personalized to the patient's exact cranio-facial dimensions. Once dimensions are calculated, ART frequency is calculated by an algorithm that is then transmitted to a headband worn by the patient three times a day.
Non-personalized ART
ART frequency randomly transmitted to a headband worn by the patient three times a day.
Locations (2)
Stanford University
Stanford, California, United States
Ohio State University
Columbus, Ohio, United States