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Selective Removal of Endometriotic Lesions Using CUSA Clarity in Ovarian Endometriomas
Sponsor: Kanazawa University
Summary
This study aims to evaluate the feasibility and tissue selectivity of a novel surgical technology, the Cavitron Ultrasonic Surgical Aspirator (CUSA) Clarity, in the management of ovarian endometriomas. Ovarian endometriomas are cysts caused by endometriosis that can damage ovarian reserve when treated by conventional surgery. In this study, ovarian cyst wall specimens are examined ex vivo using different Tissue Select settings of the CUSA device. Histopathological analyses are performed to determine whether endometriotic epithelium can be selectively removed while preserving normal ovarian tissue. The findings may contribute to developing fertility-preserving surgical approaches for women with endometriomas.
Official title: Selective Removal of Endometriotic Lesions Using CUSA Clarity in Ovarian Endometriomas: A Case-Based Histopathological Study
Key Details
Gender
FEMALE
Age Range
20 Years - Any
Study Type
OBSERVATIONAL
Enrollment
10
Start Date
2025-01-30
Completion Date
2028-03-31
Last Updated
2025-10-10
Healthy Volunteers
No
Conditions
Interventions
Cavitron Ultrasonic Surgical Aspirator (CUSA) Clarity
Ex vivo application of the Cavitron Ultrasonic Surgical Aspirator (CUSA) Clarity device to ovarian endometrioma cyst wall specimens. Tissue Select settings from 0 to 4 are used to evaluate tissue selectivity, specifically removal of endometriotic epithelium while preserving normal ovarian stroma. Samples are subsequently analyzed histopathologically.
Locations (1)
Kanazawa University Hospital
Kanazawa, Ishikawa-ken, Japan