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Safety and Efficacy of Injectable Klotho Plasmid Gene Therapy in Humans
Sponsor: Minicircle
Summary
The purpose of this study is to investigate the safety and efficacy of a gene therapy for Klotho, delivered via a nonviral plasmid in healthy adult volunteers. Additionally, this study seeks to understand the cognitive and health benefits of the Klotho gene therapy.
Official title: Evaluating the Safety and Efficacy of Injectable Klotho Plasmid Gene Therapy in Humans: An Interventional, Non-Placebo-Controlled Pilot Phase Study
Key Details
Gender
All
Age Range
23 Years - 90 Years
Study Type
INTERVENTIONAL
Enrollment
24
Start Date
2025-10-06
Completion Date
2026-08
Last Updated
2026-02-17
Healthy Volunteers
Yes
Conditions
Interventions
Injectable Plasmid Klotho Gene Therapy
Injection of plasmid-delivered Klotho gene therapy
Locations (2)
Apeiron Center
Austin, Texas, United States
GARM Clinic
Roatán, Bay Islands, Honduras