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The Effect of Thalamic Stimulation on Sleep Oscillations
Sponsor: Massachusetts General Hospital
Summary
The thalamus plays a key role in supporting sleep and is also a target of therapeutic stimulation. This project investigates when, where, and how electrical stimulation delivered to the thalamus in humans elicits or disrupts sleep oscillations. This research is a first step to better understand how current neuromodulation therapies affect sleep and may help advance toward new therapies to improve sleep for a wide range of neurological and neuropsychological disorders.
Official title: Thalamocortical Interactions and the Effect of Thalamic Stimulation on Sleep Oscillations
Key Details
Gender
All
Age Range
5 Years - 85 Years
Study Type
INTERVENTIONAL
Enrollment
50
Start Date
2025-01-06
Completion Date
2029-11-30
Last Updated
2025-10-15
Healthy Volunteers
No
Conditions
Interventions
Effect of Electrical Stimulation on Sleep
Direct electrical stimulation of thalamic nuclei and cortical structures using clinically implanted depth electrodes will allow assessing the effect of stimulation on sleep oscillations.
Locations (2)
Brigham and Women's Hospital
Boston, Massachusetts, United States
Massachusetts General Hospital
Boston, Massachusetts, United States