Clinical Research Directory

Inclusion Criteria: * Male and female subjects 15 - 70 years of age * Previous diagnosis of ADPKD (based on Ravine et al. criteria) * Class 1 A-E according to imaging classification * estimated GFR\> 45 mL/min/1.73 m2 (CKD-EPI) * Ability to provide written, informed consent Exclusion Criteria: * Class 2, according to imaging classification * A concomitant systemic disease affecting the kidney * Diabetes mellitus * Predicted urine protein excretion in \>1 g/24 hrs. and or abnormal urinalysis * Use of antioxidants, i.e., vitamins, Nrf2 activators * Patients who are part of an interventional study or taking tolvaptan