Clinical Research Directory

Inclusion Criteria: * Females with age between 30 to 60 years. (Monticciolo et al., 2021) * Females with unilateral mastectomy post three months of surgery. (Shen et al., 2023) 21 * A volume difference to the circumferential measurements between the affected and unaffected upper extremities of more volume difference\>10%. * Completed chemotherapy and/or radiation therapy. (Borman, Yaman, Yasrebi, İnanlı, \& Dönmez, 2022) Exclusion Criteria: * Systemic disorders that might contraindicate the use of sequential compression therapy i.e. chronic kidney disease with renal failure, Congestive heart failure, neurological disorders, respiratory disorders. * Presence of active cellulitis, open and partially healed wounds. * Patients with lipedema * Active or recurrent cancer (defined as \< 3 months since completion of cancer therapy) * An acute infection within the previous 4 weeks * Active venous thromboembolic edema * Pregnant women and women who are planning or nursing at study entry. * Patients who had participated in any clinical trial of an investigational substance or device during the previous 30 days * Potential patients with a cognitive or physical impairment that would interfere with appropriate use of the device. (Rockson, Whitworth, et al., 2022)