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RECRUITING
NCT07218770
PHASE1/PHASE2

A Study of REGN7041 for Active Noninfectious Uveitis in Adult Participants

Sponsor: Regeneron Pharmaceuticals

View on ClinicalTrials.gov

Summary

This study is researching an experimental drug called REGN7041 (also referred to as "study drug"). The study is focused on patients who have active inflammation inside of the eye without any signs of infection. The aim of the study is to see how safe and tolerable the study drug is. This is the first time the study drug is being tested in humans. The study is looking at several other research questions, including: * What side effects may happen from taking the study drug * How much study drug is in the blood and the fluid in the eye at different times * Whether the body makes antibodies against the study drug (which could make the study drug less effective or could lead to side effects)

Official title: A Phase 1/2a Study of REGN7041 (Anti-CD3 Monoclonal Antibody) in Participants With Active Noninfectious Uveitis Affecting the Posterior Segment

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

72

Start Date

2025-12-17

Completion Date

2028-06-28

Last Updated

2026-03-24

Healthy Volunteers

No

Interventions

DRUG

REGN7041

Administered as per the protocol

Locations (4)

Illinois Retina Associates

Oak Park, Illinois, United States

Tennessee Retina

Nashville, Tennessee, United States

Retina Consultants of Texas - Houston

Bellaire, Texas, United States

Retina Consultants of Texas

Katy, Texas, United States