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A Study to Evaluate the Efficacy and Safety of Bimekizumab in Study Participants With Palmoplantar Pustulosis
Sponsor: UCB Biopharma SRL
Summary
The purpose of this study is to evaluate the efficacy and safety of bimekizumab compared with placebo in participants with palmoplantar pustulosis (PPP).
Official title: A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study With Open-Label Extension to Evaluate the Efficacy and Safety of Bimekizumab in Study Participants With Palmoplantar Pustulosis
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
320
Start Date
2025-11-14
Completion Date
2029-11-22
Last Updated
2026-07-06
Healthy Volunteers
No
Conditions
Interventions
Bimekizumab
Study participants will receive bimekizumab at pre-specified time points.
Placebo
Study participants will receive matching placebo at pre-specified time points.
Locations (85)
Ppp001 50754
Birmingham, Alabama, United States
Ppp001 50746
Coral Gables, Florida, United States
Ppp001 50757
Auburn Hills, Michigan, United States
Ppp001 50745
Columbus, Ohio, United States
Ppp001 50202
Fairborn, Ohio, United States
Ppp001 50744
Oklahoma City, Oklahoma, United States
Ppp001 50233
Barrie, Canada
Ppp001 50354
Calgary, Canada
Ppp001 50749
Fredericton, Canada
Ppp001 50765
London, Canada
Ppp001 50740
Québec, Canada
Ppp001 50752
Red Deer, Canada
Ppp001 50750
Surrey, Canada
Ppp001 20357
Beijing, China
Ppp001 20137
Chengdu, China
Ppp001 20352
Chengdu, China
Ppp001 20350
Chongqing, China
Ppp001 20311
Guangzhou, China
Ppp001 20313
Guangzhou, China
Ppp001 20022
Hangzhou, China
Ppp001 20193
Hangzhou, China
Ppp001 20344
Jinan, China
Ppp001 20355
Jinan, China
Ppp001 20345
Shanghai, China
Ppp001 20184
Shenzhen, China
Ppp001 20136
Tianjin, China
Ppp001 20356
Xi'an, China
Ppp001 20353
Yinchuan, China
Ppp001 40881
Ústí nad Labem, Czechia
Ppp001 40886
Hellerup, Denmark
Ppp001 40067
Lyon, France
Ppp001 40874
Nice, France
Ppp001 40887
Toulon, France
Ppp001 40875
Ahaus, Germany
Ppp001 40740
Bad Bentheim, Germany
Ppp001 40515
Berlin, Germany
Ppp001 40891
Bielefeld, Germany
Ppp001 40893
Bochum, Germany
Ppp001 40356
Dresden, Germany
Ppp001 40866
Göttingen, Germany
Ppp001 40249
Kiel, Germany
Ppp001 40892
Lübeck, Germany
Ppp001 40747
Mainz, Germany
Ppp001 40177
Münster, Germany
Ppp001 40366
Rostock, Germany
Ppp001 40203
Budapest, Hungary
Ppp001 40895
Debrecen, Hungary
Ppp001 40894
Orosháza, Hungary
Ppp001 40816
Brescia, Italy
Ppp001 40567
Roma, Italy
Ppp001 40830
Rozzano, Italy
Ppp001 40626
Bialystok, Poland
Ppp001 40637
Gdansk, Poland
Ppp001 40878
Katowice, Poland
Ppp001 40915
Krakow, Poland
Ppp001 40757
Poznan, Poland
Ppp001 40396
Rzeszów, Poland
Ppp001 40743
Szczecin, Poland
Ppp001 40788
Torun, Poland
Ppp001 40604
Warsaw, Poland
Ppp001 40625
Warsaw, Poland
Ppp001 40876
Warsaw, Poland
Ppp001 40334
Wroclaw, Poland
Ppp001 40862
Wroclaw, Poland
Ppp001 20366
Anyang-si, South Korea
Ppp001 20211
Bucheon-si, South Korea
Ppp001 20214
Busan, South Korea
Ppp001 20215
Gwangju, South Korea
Ppp001 20367
Jeonju, South Korea
Ppp001 20208
Seongnam-si, South Korea
Ppp001 20104
Seoul, South Korea
Ppp001 20216
Seoul, South Korea
Ppp001 20351
Seoul, South Korea
Ppp001 20354
Seoul, South Korea
Ppp001 40750
Alicante, Spain
Ppp001 40266
Badalona, Spain
Ppp001 40885
Granada, Spain
Ppp001 40888
Madrid, Spain
Ppp001 40297
Manises, Spain
Ppp001 40889
Málaga, Spain
Ppp001 40230
Valencia, Spain
Ppp001 40868
Valencia, Spain
Ppp001 40113
London, United Kingdom
Ppp001 40880
London, United Kingdom
Ppp001 40108
Salford, United Kingdom