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Impact of Exogenous Ketones on Breathing in Healthy Volunteers
Sponsor: Johns Hopkins University
Summary
Exogenous ketones (EK) are compounds that can increase the level of ketones in the body without needing to change what an individual eats. Although EK have been researched mainly in relation to energy and exercise, there haven't been many studies focusing specifically on how EKs affect breathing using well-established scientific methods. The investigators believe that EK may help improve breathing, which could be beneficial for situations like high altitudes, sleep apnea, and exercise. To explore how EK might influence breathing, the investigators are conducting a randomized, placebo-controlled crossover study with healthy volunteers.
Official title: Impact of Exogenous Ketones on Sleep and Breathing in Healthy Volunteers
Key Details
Gender
All
Age Range
18 Years - 50 Years
Study Type
INTERVENTIONAL
Enrollment
20
Start Date
2026-03-12
Completion Date
2027-02-10
Last Updated
2026-03-31
Healthy Volunteers
Yes
Conditions
Interventions
1,3 butanediol
40 mg Ketone-IQ beverage
Placebo
Placebo (taste matched)
Locations (1)
Johns Hopkins Bayview Medical Center
Baltimore, Maryland, United States