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Weight Loss in People Living With Overweight or Obesity Following Treatment With Cagrilintide
Sponsor: Novo Nordisk A/S
Summary
This study will look at how much cagrilintide helps people with overweight or obesity lower their body weight. Cagrilintide is a new investigational medicine. Doctors may not yet prescribe cagrilintide. Participants will either get cagrilintide or placebo. Which treatment participants get is decided by chance. Participants are two times more likely to get cagrilintide than placebo. Like all medicines, the study medicine may have side effects. Possible side effects will be followed carefully during the study. For each participant, the study will last for about 1 year and 6 months.
Official title: Efficacy and Safety of Cagrilintide for Weight Management in Participants With Overweight or Obesity
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
300
Start Date
2025-11-05
Completion Date
2027-06-29
Last Updated
2026-04-08
Healthy Volunteers
No
Conditions
Interventions
Cagrilintide
Cagrilintide will be administered subcutaneously with a pen-injector as an adjunt to lifestyle intervention counselling.
Placebo
Placebo matched to cagrilintide will be administered subcutaneously with a pen-injector as an adjunt to lifestyle intervention counselling.
Locations (40)
Diablo Clinical Research, Inc.
Walnut Creek, California, United States
Univ of Colorado at Denver
Aurora, Colorado, United States
Florida Inst For Clin Res LLC
Orlando, Florida, United States
Oviedo Medical Research, LLC
Oviedo, Florida, United States
Walgreens - Store 11760
Oak Park, Illinois, United States
Midwest Inst For Clin Res
Indianapolis, Indiana, United States
StudyMetrix Research LLC
City of Saint Peters, Missouri, United States
PharmQuest Life Sciences LLC
Greensboro, North Carolina, United States
Selma Medical Associates
Winchester, Virginia, United States
CIPREC Pueyrredon
Buenos Aires, Argentina
CEDIC Centro de Investigación Clínica
CABA, Argentina
Sydney Cardiometabolic Centre
Liverpool, New South Wales, Australia
Hunter Diabetes Centre
Merewether, New South Wales, Australia
G.A. Research Associates Ltd.
Moncton, New Brunswick, Canada
Nova Scotia Hlth Halifax
Halifax, Nova Scotia, Canada
Hamilton Medical Rsrch Grp
Hamilton, Ontario, Canada
Wharton Medical Clinic Clinical Trials (Hamilton)
Hamilton, Ontario, Canada
Milestone Research
London, Ontario, Canada
Centricity Research Oshawa
Oshawa, Ontario, Canada
Centricity Research Toronto
Toronto, Ontario, Canada
Centricity Research Mirabel
Mirabel, Quebec, Canada
Centre Hospitalier Universitaire de Nantes-Hopital Nord Laennec
Saint-Herblain, France
Centre de Recherche Clinique Portes Du Sud
Vénissieux, France
InnoDiab Forschung GmbH
Essen, Germany
Wendisch - Dahl Hamburg - DZHW
Hamburg, Germany
RED-Institut für medizinische Forschung und Fortbildung GmbH
Oldenburg in Holstein, Germany
Fondazione Policlinico Universitario Agostino Gemelli IRCS
Rome, RM, Italy
AOUP Giaccone Palermo
Palermo, Sicily, Italy
A.O.U. Bologna_ Policlinico S.Orsola Malpighi
Bologna, Italy
IRCCS Ospedale San Raffaele Milano
Milan, Italy
Haukeland Universitetssykehus
Bergen, Norway
Drammen sykehus - Vestre Viken HF
Drammen, Norway
St. Olavs Hospital HF_Endokrinologisk avdeling
Trondheim, Norway
Osteo-Medic s.c. A. Racewicz, J. Supronik
Bialystok, Poland
Care Clinic Sp. z o. o.
Katowice, Poland
Terpa Sp. z o.o. Sp. k.
Lublin, Poland
NBR Polska Tomasz Klodawski
Warsaw, Poland
Oak Tree Surgery
Liskeard, Cornwall, United Kingdom
North Coast Medical Ltd
Newquay, Cornwall, United Kingdom
Brunel Medical Practice
Torquay, Devon, United Kingdom