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RECRUITING
NCT07221617
PHASE4

Oral Methadone in Cardiac Surgery

Sponsor: Mayo Clinic

View on ClinicalTrials.gov

Summary

The purpose of this study is to compare the effects of administration of oral methadone preoperatively and intravenous methadone upon induction of general anesthesia on postoperative pain for patients undergoing elective cardiac surgery.

Official title: Oral Methadone In Cardiac Surgery

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

100

Start Date

2026-01-13

Completion Date

2026-08

Last Updated

2026-01-14

Healthy Volunteers

No

Interventions

DRUG

Methadone, oral

Patients will receive 0.4mg/kg PO methadone immediately prior to transport to the operating room

DRUG

Methadone, intravenously

Patients will receive 0.3mg/kg methadone intravenously after induction of general anesthesia

Locations (1)

Mayo Clinic in Rochester

Rochester, Minnesota, United States