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COMPLETED
NCT07222098
PHASE1

A Clinical Study of Calderasib (MK-1084) With Rosuvastatin and Metformin in Healthy People (MK-1084-016)

Sponsor: Merck Sharp & Dohme LLC

View on ClinicalTrials.gov

Summary

Researchers want to learn about calderasib when given with rosuvastatin and metformin in healthy people. The goal of this study is to compare the amount of rosuvastatin and metformin in a person's body over time when given with and without calderasib

Official title: An Open-Label, 2-Period, Crossover Study to Evaluate the Effects of a Single Dose of MK-1084 on the Single-Dose Pharmacokinetics of Rosuvastatin and Metformin in Healthy Participants

Key Details

Gender

All

Age Range

19 Years - 60 Years

Study Type

INTERVENTIONAL

Enrollment

16

Start Date

2025-11-19

Completion Date

2025-12-29

Last Updated

2026-05-06

Healthy Volunteers

Yes

Conditions

Interventions

DRUG

Rosuvastatin

Oral tablet

DRUG

Metformin

Oral tablet

DRUG

Calderasib

Oral tablet

Locations (1)

Celerion ( Site 0001)

Lincoln, Nebraska, United States