Clinical Research Directory

Inclusion Criteria: * Willing to provide informed consent. * Willing to comply with all study procedures and be available for the duration of the study. * Individuals at least 50 years of age. * Enrolled in Wisconsin Registry for Alzheimer's Prevention (WRAP) or Alzheimer's Disease Research Center Clinical Core (ADRC) * Previously adjudicated as cognitively unimpaired having mild cognitive impairment (MCI), or impaired but do not meet diagnostic criteria for mild cognitive impairment or dementia (classified as "Impaired-Not MCI" by the WRAP and ADRC cohorts) at their last WRAP or ADRC study visit at the time of enrollment into this study * Have completed or able to complete amyloid and/or tau PET scans as part of a UW Alzheimer's Research Study Exclusion Criteria: * Diagnosis of dementia at the time of enrollment as determined by the most recent parent WRAP/ADRC study visit diagnostic consensus conference using standard NIA-AA 2011 diagnostic criteria. Participants who develop dementia after enrolling into this study may remain enrolled if they maintain decisional capacity and are able to follow study instructions and procedures. * Individuals who lack decisional capacity to provide informed consent as determined by significant difficulty in understanding materials and information about study procedures during recruitment and/or informed consent discussions. * Not suitable for study participation due to other reasons at the discretion of the investigators.