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NOT YET RECRUITING
NCT07224282
EARLY_PHASE1

The Effects of Ketone Supplements With Carbohydrates on Cycling Performance Above Lactate Threshold

Sponsor: University of Oklahoma

View on ClinicalTrials.gov

Summary

The goal of this clinical trial is to determine whether a ketone supplement with carbohydrates extends time to fatigue during cycling compared with a carbohydrate-only supplement in healthy, trained cyclists aged 18-55. The main questions it aims to answer are: Is the time to fatigue increased with ketone supplementation and carbohydrates compared to carbohydrates alone? Will ketone supplementation with carbohydrates produce lower blood lactate concentrations compared to carbohydrates alone? Participants will: * Perform a staged maximal cycling exercise test on a stationary bicycle. * Finger prick to obtain a drop of blood for lactate measurements. * Wear a mask connected to a metabolic cart to measure breath contents. * Perform a cycling exercise test to fatigue for at least one hour. * Consume either a ketone supplement with carbohydrates or a carbohydrate supplement during the exercise at least 4 times. * Finger prick to obtain a drop of blood to measure blood lactate, ketones, and glucose.

Official title: The Effects of R-1,3-Butanediol With Carbohydrate Supplementation on Cycling Performance Above Lactate Threshold

Key Details

Gender

All

Age Range

18 Years - 55 Years

Study Type

INTERVENTIONAL

Enrollment

15

Start Date

2025-11-17

Completion Date

2026-05-03

Last Updated

2025-11-04

Healthy Volunteers

Yes

Interventions

DIETARY_SUPPLEMENT

Ketone supplementation

30-gram carbohydrate beverage with 5 grams of R-1,3-Butanediol every 30 minutes of experimental visit

DIETARY_SUPPLEMENT

Carbohydrate

30-gram carbohydrate beverage with bitter flavoring

Locations (1)

University of Oklahoma

Norman, Oklahoma, United States