Clinical Research Directory

Inclusion Criteria: * Male and Female, age 18-70, inclusive. * Availability for the 12-week duration of the clinical research study. * Good general health at the discretion of the dental examiner or study investigators. * Minimum of 20 permanent natural teeth (excluding third molars). * Initial gingivitis index of at least 1.0 as determined by the use of the Loe and Silness Gingival Index. * Initial mean plaque index of at least 0.6 as determined by Rustogi Modification of the Navy plaque index. * Signed Informed Consent Form Exclusion Criteria: * Presence of orthodontic appliances. * Presence of partial removable dentures. * Oral pathology, chronic disease or tumor(s) of the soft or hard tissues of the oral cavity. * Advanced periodontal disease (purulent exudate, tooth mobility, and/or extensive loss of periodontal attachment or alveolar bone). * Five or more carious lesions requiring immediate restorative treatment. * Use of anticonvulsants, sedatives, tranquilizers, anti-inflammatory or daily analgesics within one month prior to the start of the study or scheduled to start such intake during the course of the study. * Use of antibiotics any time during the one-month period prior to entry into the study. * Ongoing use of medications known to affect gingival tissues (i.e. calcium channel blockers, phenytoin, cyclosporine) and/or on any prescription medicines that might interfere with the study outcome. * Participation in any other clinical study. * Self-reported pregnancy and/or breastfeeding. * Dental prophylaxis within the past three weeks prior to baseline examinations. * Current allergies and/or history of allergic reactions to oral care products, personal care consumer products, or any of their ingredients.