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RECRUITING
NCT07226284
NA

Effects of Vagal Nerve Stimulation on Leg Muscle Activity and Posture in Parkinson's Disease

Sponsor: University of Minnesota

View on ClinicalTrials.gov

Summary

This study is designed to better understand the mechanisms contributing to impaired activation of leg muscles in people with Parkinson's disease (PD) and to test if stimulation of a nerve at the neck can improve muscle activation, walking and balance.

Official title: The Effects of Vagus Nerve Stimulation on Intrinsic Lower Leg Spinal Motoneuron Excitability in Parkinson's Disease.

Key Details

Gender

All

Age Range

21 Years - 76 Years

Study Type

INTERVENTIONAL

Enrollment

75

Start Date

2026-02-10

Completion Date

2029-01

Last Updated

2026-02-13

Healthy Volunteers

Yes

Interventions

DEVICE

Vagal nerve stimulation

The gammaCore non-invasive vagus nerve stimulator (nVNS) is a hand-held portable device that is used to apply electrical stimulation to the vagus nerve via two electrodes.

OTHER

No intervention

No nVNS is applied in the baseline experiment. Sham nVNS is applied for experiment two

Locations (1)

Movement Disorders Laboratory

Minneapolis, Minnesota, United States