Clinical Research Directory

Inclusion Criteria: 1. \>= 18 years old 2. Diagnosis of a primary brain tumor OR #3. Not both #2 and #3. 3. Diagnosis of primary solid tumor and secondary involvement of the brain 4. If the patient has brain metastases: fewer than 5 brain metastases (post-operative and definitive allowed), none \> 1 cm in max diameter. 5. Candidate for standard of care / usual care (SOC) focused brain radiotherapy. 6. No prior brain radiotherapy, including whole brain radiotherapy. 7. Eastern Cooperative Oncology Group (ECOG) functional score 0 or 1. 8. Estimated life expectancy post-treatment of \> 2 years. Exclusion Criteria: 1. Diagnosis of neurodegenerative disease (Alzheimer's disease, Parkinson's disease). 2. Diagnosis of memory disorder pre-treatment. 3. Leptomeningeal disease or disease involving either hippocampus.