Clinical Research Directory

Eligibility Criteria * Scheduled to undergo ultrasound guided nsPFA as standard of care * Age 18 to 80 years. * Capable of providing independent consent. * Presence of biopsy-confirmed benign thyroid nodule , defined as one of the following: * Benign FNA X 2 or * Benign US guided FNA X 1 + benign thyroid nodule ultrasound appearance (TI-RADS 2) or * Benign FNA X 1 and radiographic/laboratory evidence of functional nature * Nodule measuring \>2cm in greatest dimension * Presence of compressive symptoms reasonably attributable to thyroid nodule (i.e. pressure sensation, dysphagia, dysphonia, respiratory distress) * No abnormal cervical lymph nodes during screening visit . Exclusion Criteria * Age \<18 * Patients considered unsuitable for nsPFA by the treating physician