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Human Thalamus in Propagation of Temporal Lobe Seizures and Memory Formation
Sponsor: Stanford University
Summary
The goal of the study is to examine how two key subregions of the human thalamus (ANT and PLV) are connected with other brain structures (Aim 1), how seizures involve the two thalamic subregions differently and how the map of cortico-thalamic ictal propagation matches the intrinsic connectivity maps identified in the same individuals (Aim 2), and the effect of ANT and PLV stimulations on memory formation (Aim 3).
Key Details
Gender
All
Age Range
18 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
100
Start Date
2024-09-01
Completion Date
2029-08
Last Updated
2025-11-12
Healthy Volunteers
No
Conditions
Interventions
Cognitive experiment
Record brain activity during memory encoding
Electrical stimulation of the brain
Measure accuracy and reaction time during cognitive tasks
Locations (1)
Stanford Hospital
Stanford, California, United States