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RECRUITING
NCT07226934
NA

An AI-Generated, Personalized Question Prompt List Intervention for Patients With Hematologic Cancers

Sponsor: Washington University School of Medicine

View on ClinicalTrials.gov

Summary

The goal of this study is to evaluate the feasibility and preliminary efficacy of an artificial intelligence (AI)-generated personalized question prompt list (a list of suggested questions to ask during outpatient appointments) for patients with hematologic cancers. The intervention will involve tailoring a standardized prompt to patients' individual characteristics and concerns. This prompt will then be used to ask Washington University's (WashU) HIPAA compliant ChatGPT to generate personalized question lists for outpatient appointments. Analyses will assess the impact of personalized QPLs on patients' question-asking behavior; communicative self-efficacy; and self-reported amount and satisfaction with information obtained about their disease and its treatment. Sub-analyses will explore patterns in questions generated by WashU ChatGPT. Patients will also provide feedback pertaining to the perceived helpfulness and ease-of-use of WashU-ChatGPT-generated question lists, as well as their attitudes and intentions regarding use of AI chatbots and whether they would engage in pre-appointment AI-assisted question brainstorming independently in the future.

Official title: Feasibility and Preliminary Efficacy of GPT-QPL: An AI-Generated, Personalized Question Prompt List Intervention for Patients With Hematologic Cancers

Key Details

Gender

All

Age Range

20 Years - 99 Years

Study Type

INTERVENTIONAL

Enrollment

40

Start Date

2025-12-26

Completion Date

2026-04-30

Last Updated

2026-03-25

Healthy Volunteers

No

Interventions

OTHER

GPT-QPL

A research team member will generate a QPL that is personalized to the patient's demographics (from EHR screening and Baseline Demographic Survey) and concerns (from Distress Thermometer Problem Checklist and Interview).

Locations (1)

Washington University School of Medicine

St Louis, Missouri, United States