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Evaluating the Status of Complex Aneuploidy to Locate Additional Transferrable Embryos
Sponsor: Shady Grove Fertility Reproductive Science Center
Summary
This study aims to evaluate the reproductive potential of embryos classified as "complex aneuploid" (involving three or more abnormal chromosomes) or "chaotic" (six or more abnormal chromosomes) through preimplantation genetic testing for aneuploidy (PGT-A). Specifically, we seek to determine whether embryos initially reported as having multiple chromosomal abnormalities might still have the potential for normal chromosomal composition, the opportunity for transfer, and ultimately, the potential to achieve a live birth through re-biopsy and reanalysis. Key Information: This portion of the study seeks your consent for the re-biopsy and genetic reanalysis of the embryos only. It does not yet include consent for potential future transfer. Participation remains completely voluntary, and your decision will not affect your current or future care. We deeply appreciate your support and commitment to advancing fertility research.
Official title: ESCALATE: Evaluating the Status of Complex Aneuploidy to Locate Additional Transferrable Embryos
Key Details
Gender
All
Age Range
Any - Any
Study Type
OBSERVATIONAL
Enrollment
280
Start Date
2025-11-01
Completion Date
2026-06
Last Updated
2025-11-12
Healthy Volunteers
Yes
Conditions
Locations (12)
IVF Florida Reproductive Associates
Margate, Florida, United States
Shady Grove Fertility
Atlanta, Georgia, United States
Fertility Center of Illinois
Highland Park, Illinois, United States
Shady Grove Fertility
Rockville, Maryland, United States
Shady Grove Fertility
Towson, Maryland, United States
Shady Grove Fertility
Cary, North Carolina, United States
Shady Grove Fertility
Cary, North Carolina, United States
Shady Grove Fertility
Chesterbrook, Pennsylvania, United States
Shady Grove Fertility
Fairfax, Virginia, United States
Shady Grove Fertility
Norfolk, Virginia, United States
Shady Grove Fertility
Richmond, Virginia, United States
SGFertility Chile Medicina Reproductiva
Santiago, Santiago Metropolitan, Chile