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Fixed-Dose Combinations Pragmatic Randomized Implementation Trial for Blood Pressure Control
Sponsor: Brigham and Women's Hospital
Summary
The proposed study is an effectiveness-implementation hybrid type II trial designed to evaluate the impact of provider- and patient-directed interventions on FDC use. The trial will test the effectiveness of theory-driven nudges tailored to address provider and patient barriers. All interventions will be pharmacist-driven, with pharmacists delivering information via nudges to providers and via nudges or more intensive interventions (i.e., CPA) to patients. Data to evaluate outcomes will be extracted from electronic health records.
Official title: Pharmacy-led Intervention to Increase the Adoption of Fixed-dose Single Pill Blood Pressure Lowering Medications: Hybrid Effectiveness-Implementation Trial
Key Details
Gender
All
Age Range
18 Years - 80 Years
Study Type
INTERVENTIONAL
Enrollment
720
Start Date
2026-05-01
Completion Date
2027-05-31
Last Updated
2026-03-27
Healthy Volunteers
No
Conditions
Interventions
Provider nudge
Pharmacists will deliver targeted nudges to providers through clinical decision support integrated into the electronic health record (EHR)
Patient nudge
Patients will receive pharmacist-delivered nudges (e.g., text messages) 1-7 days before their visit to encourage fixed-dosed combinations
Pharmacist Virtual Visit
Patients will receive pharmacist counseling and prescribing delivered via virtual encounters after their visit