Clinical Research Directory
Browse clinical research sites, groups, and studies.
Quantification of Calcinosis Cutis Disease Burden Using Computed Tomography Images
Sponsor: Yale University
Summary
The main purpose of this study is to develop sensitive radiographic measurement techniques that can be used as outcome measures along with patient-reported outcome instruments in clinical trials of calcinosis cutis treatments, and potentially be used to assess disease course and treatment response in clinical practice. The goal is to test the performance of the software.
Official title: Quantification of Calcinosis Cutis Disease Burden in Patients With Systemic Sclerosis Using Computed Tomography Images
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
56
Start Date
2025-10-14
Completion Date
2026-07
Last Updated
2026-02-17
Healthy Volunteers
No
Conditions
Interventions
Sodium Thiosulfate (STS)
Calcinosis cutis treatment, 25% STS topical cream, Twice daily for 6 months
Sodium Thiosulfate Injection
calcinosis cutis treatment, 25% STS intradermal injection, once monthly for 6 months
Locations (1)
Yale Scleroderma Program
New Haven, Connecticut, United States