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NOT YET RECRUITING
NCT07231445
PHASE1

Study of ZG006 in Combination With PD-1/PD-L1 Immune Checkpoint Inhibitors as First-Line Standard Therapy in Participants With Extensive Stage Small-Cell Lung Cancer

Sponsor: Suzhou Zelgen Biopharmaceuticals Co.,Ltd

View on ClinicalTrials.gov

Summary

This is a randomized, multicenter, phase Ib study to evaluate the safety and efficacy of ZG006 combined with PD-1/PD-L1 immune checkpoint inhibitors (±chemotherapy) as first-line therapy in Participants with extensive stage small cell lung cancer.

Official title: A Phase Ib Study Evaluating the Safety and Efficacy of ZG006 in Combination With PD-1/PD-L1 Immune Checkpoint Inhibitors as First-Line Standard Therapy in Participants With Extensive Stage Small-Cell Lung Cancer

Key Details

Gender

All

Age Range

18 Years - 75 Years

Study Type

INTERVENTIONAL

Enrollment

100

Start Date

2026-03

Completion Date

2027-12

Last Updated

2026-03-04

Healthy Volunteers

No

Interventions

DRUG

ZG006

ZG006 will be administered as an IV infusion.

DRUG

Serplulimab

Serplulimab will be administered as an IV infusion.

Locations (1)

Shanghai Chest Hospital

Shanghai, Shanghai Municipality, China